The Los Angeles Business Journal’s index of largest local public companies fell slightly for the week ended Jan. 28, as the markets were hurt by a move to less risky investments due to unrest in Egypt.

The weighted LABJ index fell 0.29 percent to 122.40, with decliners outpacing gainers 102 to 68.

American Apparel Inc. fell 23.4 percent to $1.05 on word that the Los Angeles apparel maker’s second-largest shareholder, billionaire Ronald Burkle, had reduced his stake from 6 percent to 4.7 percent.

MannKind Corp., still hurting from U.S. Food and Drug Administration rejection of its inhaled insulin treatment, lost ground for a second week, falling 18 percent to $5.04.

Live Nation Entertainment Inc. dropped 7.7 percent to $10.26 after the Beverly Hills concert and ticketing company cut its annual profit forecast due to settlement costs from a class-action lawsuit against its Ticketmaster division.

Among the biggest gainers was Simulations Plus Inc., which jumped 17.4 percent to $10.10 after the Lancaster scientific software developer announced a five-year research agreement with the U.S. Food and Drug Administration.

OSI Systems Inc. rose 10 percent to $37.27 after the Hawthorne maker of security screening systems and medical equipment reported a better-than-expected fiscal second quarter.

Molina Healthcare Inc. gained 8 percent to $30.47 after the Long Beach health insurer provided strong revenue guidance for the next two years.