Stocks plunged on Thursday as a jump in oil prices above $48 a barrel fomented concern about higher energy costs and General Motors Corp. provided a weaker profit outlook.

The Dow Jones Industrial Average suffered its largest one-day percentage decline since Nov. 19 and the Nasdaq Composite and S & P; 500 indexes felt their largest respective one-day drops since Jan 4.

The Dow Jones Industrial Average fell 111.95 points, or 1.1 percent, to end at 10,505.83. The Standard & Poor’s 500 fell 10.25 points, or 0.9 percent, to close at 1,177.45. The Nasdaq Composite fell 21.97 points, or 1.1 percent, to finish at 2,070.56.

Among local movers, First Regional Bancorp Inc. jumped 10.4 percent to $62.40, after the L.A.-based bank holding company posted healthy quarterly earnings. First Regional Bancorp reported net income of $4.3 million ($1.06 per diluted share) for the fourth quarter ended Dec. 31, versus $1.3 million (45 cents) in the year-ago period.

Interactive game producers Activision Inc. and THQ Inc. both rose on a report by WR Hambrecht + Co. Activision gained 7.2 percent to $21.18 after Hambrecht analyst Bill Lennan said he expects the Santa Monica company to meet his revenue and earnings per share estimates of $615 million and 55 cents, respectively, for the December quarter.

THQ Inc. rose 3.1 percent to $21.92. Lennan said he expects the Calabasas Hills-based video game publisher to slightly beat his quarterly revenue estimate of $333 million and earnings per share estimate of $1.14.

And shares of Chatsworth-based nutrition brand Natrol Inc. fell 13.7 percent to $2.65.