The Los Angeles Business Journal’s index of the 200 largest local public companies closed down for the week ended July 10, but continued worries over the economy keep many investors out of overall markets.

The weighted LABJ index for a second straight week closed down 1.5 percent to 115.82, with decliners outpacing gainers 124 to 49.

Among top gainers was CalAmp Corp., which jumped more than 25 percent to $1 after the Camarillo wireless communications components maker reported better-than-expected first quarter earnings.

Joe’s Jeans Inc. gained 16 percent to 77 cents after the Commerce designer denim maker said it signed a new license agreement with Kids Jeans LLC to manufacture and distribute products for infants, girls and boys.

Amgen Inc. rose 12 percent to $58.81 after the Thousand Oaks biotech announced strong positive results for its experimental osteoporosis drug denosumab, which is undergoing U.S. Food and Drug Administration review.

Among the largest decliners was Macerich Co., which dropped 12 percent to $14.96 after Stifel Nicolaus initiated coverage on the Santa Monica shopping center owner with a “hold” recommendation.