Hollywood animation studio Titmouse Inc. is roaring into the big time with an unusual new sitcom.

“Son of Zorn,” slated to Fox’s Sunday night lineup next month, will be a mix of live action and animation and represents the highest-profile project yet for the 400-employee company.

Formed in 2000 by former “Beavis and Butthead” animator Chris Prynoski, Titmouse has previously worked on the “Guitar Hero” video game, Budweiser and Honda commercials, and animated cable TV shows such as “Afro Samurai” and “The Venture Bros.”

But this comedy about an animated He-Man-like warrior trying to reconnect with his human ex-wife and teenage son in Orange County is the first network primetime show for Titmouse.

It takes six to eight weeks for the 50 Titmouse employees working on “Son of Zorn” to complete the animation on each episode, which features Jason Sudeikis as the voice of Zorn and Cheryl Hines as his ex-wife.

“We use digital animation software, give the character different expressions and make sure his eye line matches that of the human actors,” said Jennifer Ray, a line producer at Titmouse.

The company has offices in New York and Vancouver but the headquarters and majority of employees are in Hollywood where “Son of Zorn” is made.

The show was previewed a week ago at Comic-Con International in San Diego, where Eric Appel, the sitcom’s executive producer, called it a “unique, bold, and cool show and that’s largely thanks to the amazing staff at Titmouse.”

– Sandro Monetti