The Dow Jones industrial average fell 108 points in Monday trading to close at 17,791.

The S&P 500 fell 10 points to 2,084.

The Nasdaq fell 21 points to 5,030.

The LABJ Stock Index was flat at 231.

Gainers and Losers

Monday’s biggest local gainer was Kythera Biopharmaceuticals Inc. The Calabasas drug developer’s shares rose 9 percent on the day, closing at $59.75.

Monday’s biggest loser was Ixia, another Calabasas company. Shares of the networking software firm fell 4 percent, closing at $12.44.