Glendale-based Apollo Medical Holdings Inc. was the week’s biggest gainer jumping 33.3 percent to close the week at $10. Arrowhead Pharmaceuticals Inc. also posted big gains. The Pasadena biotech firm ticked up 26.4 percent to close at $1.96. Downtown advertising firm Social Reality Inc. was the week’s biggest loser, dropping 18.6 percent to close at $5.