Analyst upgrades and brighter earning boosted some local stocks while poor earnings and short selling stung others.

Shares in MannKind Corp. gained 21 percent for the week to $14.25. The surge came after a Banc of America Securities analyst started coverage of the Valencia-based biopharmaceutical company with a “buy” rating.

Hansen Natural Corp. also got a boost from an analyst. Goldman, Sachs & Co. upgraded the Corona-based beverage maker’s rating from “neutral” to “buy,” sending shares up 12 percent to $43.90.

Virco Manufacturing Corp. got a boost from Wall Street after the Torrance-based school furniture maker said it had narrowed its first-quarter loss. Shares gained 8 percent to $6.75 for the week.

On the losing end was Van Nuys-based clothing manufacture Cherokee Inc., which lost 11 percent for the week after reporting dips in both first quarter profit and sales. Shares closed at $43.11.

IndyMac Bancorp Inc. also lost ground for the week, dropping 7 percent to $32.61 due to short selling of the stock, according to reports. The Pasadena-based lender had been on the rebound after reporting better-than expected earnings at the end of April, gaining more than 36 percent.