The Dow Jones industrial surged 619 points in Wednesday trading to close at 16,286, erasing much of the previous two days’ losses.

The S&P 500 rose 73 points to 1,941.

The Nasdaq rose 191 points to 4,698.

The LABJ Stock Index rose eight points to 218.

Gainers and Losers

Among stocks trading above $1, Santa Monica Web publisher Demand Media was Wednesday’s biggest local gainer. Shares of the company rose 11 percent on the day, closing at $4.68.

Wednesday’s biggest loser was billionaire Patrick Soon-Shiong’s clinical-stage immunotherapy firm NantKwest Inc. Shares of the company fell 7 percent on the day to close at $19.30.