Sony Pictures Entertainment is laying off 450 people, more than 6.5 percent of its workforce, as part of a studio-wide belt-tightening blamed on the growth of piracy and changing media consumption patterns, particularly the ongoing downturn in DVD sales.

In a memo to Sony Pictures' roughly 6,800 employees Monday, Chairman Michael Lynton and Co-Chairman Amy Pascal said most of the layoffs would hit the home entertainment and information technology divisions in the U.S.

But all business units would be affected, they said, including motion pictures, television, digital production and corporate operations. Along with the layoffs, the studio is eliminating about 100 open positions. This will be the second time in a year that Sony Pictures has cut its workforce. Last March it laid off 250 people and scrapped 100 open positions.

Industrywide, combined sales of DVDs and high-definition Blu-ray discs fell more than 13 percent in the U.S. last year.

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