Cedars-Sinai Medical Center plans to lay off nearly 190 employees – about 1 percent of staff – in order to streamline operations.

The Beverly Grove hospital wrote in a letter filed June 7 with the state Employment Development Department that 187 workers could lose their jobs.

The workforce reduction is likely to hit a number of different departments at the hospital, from clinical lab scientists to pharmacy workers to nursing and a health systems manager, among others.

The notice to the state gave a June 1-to-Aug. 10 timeline on the layoffs, which were attributed to the “needs of an evolving health care climate.”

“In keeping with Cedars-Sinai’s mission and commitment to meet our community’s need for extraordinary healthcare that is accessible, affordable and high quality, we continually re-examine the way we operate across the institution to become more efficient,” said Andrew Ortiz, a senior vice present of human resources and organization development, in his letter to the state.

“As a result,” he added, “we have determined that we need to reduce staff in some areas.”

Cedars-Sinai employs more than 15,000 workers at the largest hospital in Los Angeles, with 885 staffed beds. It admits more than 47,000 patients a year, and sees nearly 2,000 outpatients each day.

Cedars-Sinai took in $2.9 billion in net patient revenue last year, according to a recently published Business Journal report, down from $3 billion in 2016. Its operating margin was 10 percent.

A hospital representative said the number of layoffs could be less than the total reported to the state as it seeks to shift some employees whose positions are affected into other jobs.

“We do not expect these changes to alter the quality of care we provide to our patients,” Cedars-Sinai said in a statement. “We know that change can be difficult and disruptive.

“We will continue to treat all our employees in a manner that aligns with Cedars-Sinai’s values. We are committed, as always, to finding the best solutions for all our employees.”